Communications in Humanities Research ISSN: 2753-7072
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Research Article

Instrumental Behavior in Pavlovian-instrumental Transfer for Depression Therapy

Yanwei XuSuchow University*

* Corresponding author: [email protected]

Abstract

The mental condition is closely linked with people’s instrumental behavior, which allows us to adapt to the external environment. Rely on the positive valence system, the habits and goal or value seeking behavior is linked with the instrumental behavior and the influence of environmental cues. While depression patients build up an aversive Pavlovian-instrumental transfer and form a biased emotional state. The Pavlovian-to-instrumental transfer (PIT) was influenced by the environment and was reflected in biological chemistry level. Also, in the safety learning and exposure therapy, instrumental behavior has become a fundamental factor of generation of safety signals to help ease fear and anxiety. It makes exposure therapy possible. All of them are revealing that by changing instrumental behavior, it may be able to change patients’ mental condition and contribute to depression therapy. In the future, simple and effective instrumental behavior may be able to get into therapy and recover procedure of all kinds of mental disorders.

Keywords: instrumental behavior; depression therapy; environmental cues; Pavlovian-instrumental transfer (PIT); positive valence system
Published: February 21, 2025
DOI: 10.54254/2753-7064/2024.21058
Volume: CHR Vol.56
pp. 24-30
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References

  1. Cartoni, E., Balleine, B., & Baldassarre, G. (2016). Appetitive Pavlovian-instrumental transfer: A review. Neuroscience and Biobehavioral Reviews, 71, 829-848. https://doi.org/10.1016/j.neubiorev.2016.09.020
  2. Nord, C. L., Lawson, R. P., Huys, Q. J. M., Pilling, S., & Roiser, J. P. (2018). Depression is associated with enhanced aversive Pavlovian control over instrumental behavior. Scientific Reports, 8(1), 12582-10. https://doi.org/10.1038/s41598-018-30828-5
  3. Metts, A., Arnaudova, I., Staples-Bradley, L., Sun, M., Zinbarg, R., Nusslock, R., Wassum, K. M., & Craske, M. G. (2022). Disruption in Pavlovian-instrumental transfer as a function of depression and anxiety. Journal of Psychopathology and Behavioral Assessment, 44(2), 481-495. https://doi.org/10.1007/s10862-021-09941-9
  4. Geurts, D. E. M., Huys, Q. J. M., den Ouden, H. E. M., & Cools, R. (2013). Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of Neuroscience, 33(48), 18932–18939. https://doi.org/10.1523/JNEUROSCI.2749-13.2013
  5. Thurston, M. D., & Cassaday, H. J. (2022). Safety Learning in Anxiety, Pavlovian Conditioned Inhibition and COVID Concerns. Frontiers in Psychology, 13, 866771–866771. https://doi.org/10.3389/fpsyg.2022.866771
  6. Burton, T. J., & Balleine, B. W. (2022). The positive valence system, adaptive behavior, and the origins of reward. Emerging Topics in Life Sciences, 6(5), 501–513. https://doi.org/10.1042/ETLS20220007
  7. Corr P. J. (2004). Reinforcement sensitivity theory and personality. Neuroscience and biobehavioral reviews, 28(3), 317–332. https://doi.org/10.1016/j.neubiorev.2004.01.005
  8. Cools, R., Robinson, O. J., & Sahakian, B. (2008). Acute tryptophan depletion in healthy volunteers enhances punishment prediction but does not affect reward prediction. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 33(9), 2291–2299. https://doi.org/10.1038/sj.npp.1301598
  9. Cools, R., Roberts, A. C., & Robbins, T. W. (2008). Serotoninergic regulation of emotional and behavioral control processes. Trends in cognitive sciences, 12(1), 31–40. https://doi.org/10.1016/j.tics.2007.10.011
  10. Daw, N. D., & Dayan, P. (2014). The algorithmic anatomy of model-based evaluation. Philosophical Transactions of the Royal Society B: Biological Sciences, 369(1655), 20–20130478. https://doi.org/10.1098/rstb.2013.0478
  11. Anderson, M. L., & Oates, T. (2007). A Review of Recent Research in Metareasoning and Metalearning. The AI Magazine, 28(1), 7–16. https://doi.org/10.1609/aimag.v28i1.2025
  12. Huys, Q. J. M., Daw, N. D., & Dayan, P. (2015). Depression: A Decision-Theoretic Analysis. Annual Review of Neuroscience, 38(1), 1–23. https://doi.org/10.1146/annurev-neuro-071714-033928
  13. Huys, Q. J. M., Gölzer, M., Friedel, E., Heinz, A., Cools, R., Dayan, P., & Dolan, R. J. (2016). The specificity of Pavlovian regulation is associated with recovery from depression. Psychological Medicine, 46(5), 1027–1035. https://doi.org/10.1017/S0033291715002597
  14. Garbusow, M., Ebrahimi, C., Riemerschmid, C., Daldrup, L., Rothkirch, M., Chen, K., Chen, H., Belanger, M. J., Hentschel, A., Smolka, M. N., Heinz, A., Pilhatsch, M., & Rapp, M. A. (2022). Pavlovian-to-instrumental transfer across mental disorders: A review. Neuropsychobiology, 81(5), 418-437. https://doi.org/10.1159/000525579
  15. Lopizzo, N., Bocchio Chiavetto, L., Cattane, N., Plazzotta, G., Tarazi, F. I., Pariante, C. M., Riva, M. A., & Cattaneo, A. (2015). Gene-environment interaction in major depression: focus on experience-dependent biological systems. Frontiers in Psychiatry, 6, 68–68. https://doi.org/10.3389/fpsyt.2015.00068